Daridorexant, a dual orexin receptor antagonist approved by the FDA in January 2022 for insomnia disorders, improved sleep outcomes at doses of 25 mg or 50 mg with a favorable safety profile, …
Rosacea, poor sleep quality and obstructive sleep apnea: a commentary on potential interconnected features
Although rosacea is classically considered a skin disorder, recent evidence shows that it is emerging as a systemic vascular disease. The classical symptoms of burning, intense erythema and flushing could …
Efficacy and Acceptability of Intermittent Aerobic Exercise on Polysomnography-Measured Sleep in People With Rheumatoid Arthritis With Self-Reported Sleep Disturbance: A Randomized Controlled Trial
This study’s objective was to investigate the efficacy and acceptability of intermittent aerobic exercise training on sleep parameters, fatigue, pain, depressive symptoms, physical function, and cardiorespiratory fitness in people with …
Effect of sleep surgery on blood pressure in adults with obstructive sleep apnea: A Systematic Review and meta-analysis
This meta-analysis evaluates the effect of sleep surgery on blood pressure (BP) in adults with OSA. The study protocol was registered on PROSPERO (CRD42020154425). The PubMed, MEDLINE, EMBASE, and Cochrane …
Lower-Sodium Oxybate Shows Benefit in Idiopathic Hypersomnia
Newly approved treatment improves scores on sleepiness scale Lower-sodium oxybate showed efficacy in treating symptoms of idiopathic hypersomnia in a phase III randomized withdrawal trial. Compared with participants receiving lower-sodium oxybate, those …
Patient characteristics as predictors of sleep disturbances in multimorbid primary care patients – A secondary analysis
The aim of the study was to identify patient characteristics (adult attachment, health status, number and severity of chronic conditions, social support) predictive sleep disturbances after 12 months.In a secondary analysis …
A Randomized Controlled Trial of Sleep Study Surveillance with Targeted APAP Therapy for Obstructive Sleep Apnea in Pregnancy
To determine effects of targeted autoregulated positive airway pressure (APAP) in women at risk for obstructive sleep apnea (OSA) on adverse pregnancy outcomes (APOs), cost, and natural history of OSA.Pregnant …
Neurological outcomes following awake and asleep craniotomies with motor mapping for eloquent tumor resection
Cortical mapping has been used as a tool to ensure maximal safe resection of intracranial tumors for several decades. Post-surgical motor and language deficits, including seizures, weakness, aphasia, and dysarthria …
Risk Factors for Obstructive Sleep Apnea in Cystic Fibrosis
Despite emerging data that suggest a high frequency and severity of obstructive sleep apnea (OSA) among patients with cystic fibrosis (CF), few of them are referred for polysomnography. Little is …
A Systematic Review and Meta-analysis of Participants on Obstructive Sleep Apnea and Lung Cancer
Lung cancer was the most frequent disease in men and the main cause of cancer deaths in 2020. Even though obstructive sleep apnea (OSA) is carcinogenic, epidemiological research is mixed. …