A multiple sleep latency test (MSLT) with occurrence of sleep onset REM periods (SOREMP) is considered one of the central diagnostic criteria for narcolepsy according to the International Classification of …
Sleep Neurology’s Toolkit at the Crossroads: Challenges and Opportunities in Neurotherapeutics Lost and Found in Translation
We find ourselves at our present crossroads with a well-traveled toolkit, perhaps too well worn but with aspirational hopes and dreams for the field of sleep neurotherapeutics. This volume is …
Parthenogenetic mosaicism: generation via second polar body retention and unmasking of a likely causative PER2 variant for hypersomnia
Background: Parthenogenetic mosaicism is an extremely rare condition identified only in five subjects to date. The previous studies indicate that this condition is mediated by parthenogenetic activation and is free from …
European guideline and expert statements on the management of narcolepsy in adults and children
Background and aim: Narcolepsy is an uncommon hypothalamic disorder of presumed autoimmune origin that usually requires lifelong treatment. This paper aims to provide evidence-based guidelines for the management of narcolepsy …
AHA News: Getting Better Overall Sleep Might Be the Key to Better Health
Improving your overall sleep health could help lower your risk for high blood pressure, diabetes, obesity and other cardiovascular threats, according to new research. Experts already knew a lack of …
There May Be a ‘Best Bedtime’ for Your Heart
Is there an ideal time to go to bed every night if you want to dodge heart disease? Apparently there is, claims a new study that found hitting the sack …
Sleep Onset Timing Linked to Risk of Developing CVD
There is an association between sleep onset timing and the risk of developing cardiovascular disease (CVD), according to a study published online Nov. 9 in the European Heart Journal: Digital Health. …
Cognitive Behavioral Therapy for Insomnia has sustained effects on insomnia, fatigue, and function among people with chronic heart failure and insomnia: The HeartSleep Study
Study objectives: Insomnia is common among adults with chronic heart failure (HF) and associated with daytime symptoms and decrements in function. The purpose of this randomized controlled trial (RCT) was to …
Prevalent, Incident, and Persistent Insomnia in a Population-Based Cohort Tested Before (2018) and During the First-Wave of COVID-19 Pandemic (2020)
Study objectives: High rates of sleep and mental health problems have been reported during the COVID-19 pandemic, but most of the evidence is retrospective without pre-pandemic data.This study documented rates of …
Insomnia Tied to Raised Risk of Aneurysm
Researchers may have unearthed a surprising risk factor for often-fatal brain bleeds: Sleepless nights. In a study of about 70,000 adults, researchers found that people with a genetic predisposition to …